researchers have identified a chromosome region that is the source of genetic events that give rise to neuroblastoma, an often fatal childhood cancer. The investigators found that common DNA ...

New gene for childhood cancer neuroblastoma is discovered Date: December 1, 2010 Source: Children's Hospital of Philadelphia Summary: Pediatric cancer researchers have identified variations in a ...

Scientists have discovered gene mutations that are the main cause of the inherited version of the childhood cancer neuroblastoma. In addition, the researchers found that the same mutations play a ...

They found two common gene variants associated with neuroblastoma, both in the 6q16 region of chromosome 6. One variant is within the HACE1 gene, the other in the LIN28B gene.

May 8 -- WEDNESDAY, May 7 (HealthDay News) -- For the first time, a gene linked to the often fatal childhood cancer neuroblastoma has been identified, researchers report. "This is the first paper ...

“Properly defining risk level helps us to avoid the twin pitfalls of undertreating or overtreating any given child with neuroblastoma,” added Maris. However, little was known about genetic ...

The aetiology of neuroblastoma is unknown, but it seems unlikely that environmental exposures are important. A subset of patients inherits a genetic predisposition to neuroblastoma, and these ...

The researchers were also able to identify an instability in the number of gene copies present in neuroblastoma cells. In some cases, cancer cell clones showed early divergence from the primary tumor, ...

Genetic sequencing ensures that your child receives the therapies that are likely to be most effective, with the fewest side effects. MSK Offers Every Treatment Available for Neuroblastoma Not all ...

In the present study, the feasibility of a tumor-selective gene therapy approach was studied in neuroblastoma cells. Neuroblastoma is a neoplastic disease of very young children that derives from ...

Patients with high-risk neuroblastoma tend to be older than 18 months at diagnosis, have amplification of the MYCN gene, and often have metastatic disease. Their treatment involves a prolonged ...

Pediatric cancer researchers have identified variations in a gene as important contributors to neuroblastoma, the most common solid cancer of early childhood. The study team, led by researchers at ...