However; single nucleotide polymorphism (SNP) genotyping often remains dependent on arrays, leaving genotyping and NGS ...

This series highlights the breadth of next–generation sequencing applications and the importance of the insights that are being gained through these methods.

The fundamental importance of the genome to biological systems and their function makes next-generation sequencing (NGS) an extremely versatile tool used widely in research, clinical and industrial ...

The majority of patients with the most common advanced or metastatic cancers in the United States do not undergo ...

Eliminating errors in next-generation DNA sequencing has proved challenging. Here we present error-correction code (ECC) sequencing, a method to greatly improve sequencing accuracy by combining ...

Next generation sequencing enables researchers to sequence DNA and RNA much more quickly and cheaply than an older technology called Sanger sequencing. The technology is revolutionizing genomics ...

In next-generation sequencing, the importance of short-read technology is unquestioned, but other technologies matter, too. These other technologies include long-read technology, single-cell ...

Next generation sequencing can also detect mutations in the microbes’ genome, potentially explaining therapy failures or vaccine-escaping mutants. It also offers an unbiased and culture-free way ...

About three decades ago, the Sanger and Maxam-Gilbert methods revolutionized the biomedical world. Sequencing of the 5,386-base bacteriophage PhiX174 in 1977 represented a memorable moment in ...

Next-generation sequencing (NGS) provides researchers from various scientific fields the ability to cast a wide net and explore complex pathways and biological processes. With NGS, scientists can take ...

In this interview, NewsMedical speaks with Jeff Hawkins, CEO of Quantum-Si, about the challenges of conventional proteomic methods, as well as how next-generation protein sequencing is ...

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