Over the past decade, DNA sequencing throughput has increased over 50-fold. Advances in DNA sequencing have enabled logarithmic growth of data points and breadth in coverage of an individual ...

What is next-generation sequencing? Next-generation sequencing (often noted as NGS), describes the high-throughput technologies that can now determine the sequence of a given nucleic acid strand, such ...

The technologies and chemistries underlying next-generation sequencing of DNA are evolving rapidly. This review describes the three main approaches to obtaining a genetic diagnosis through next-gen ...

Dr. Issa’s group uses next-generation sequencing to study DNA methylation and histone-modification changes that occur during aging or in response to therapeutic agents used in cancer treatment.

Powerful new applications of what is known as next-generation sequencing are now helping with identification of degraded ...

Next generation sequencing (NGS), often referred to as massively parallel sequencing or deep sequencing, refers to a DNA sequencing technology that enables sequencing of millions of small DNA ...

Since the completion of the Human Genome Project in 2003, there have been a slew of significant technological developments that have allowed the sequencing of entire genomes for just a few thousand ...

Over the past fifteen years, next-generation DNA sequencing has transformed every aspect of the life sciences. However, genetics is only one component of human disease.

The overarching goals of the workshop are to (1) examine the known and expected benefits, and potential harms, of the widespread utilization of newborn DNA sequencing, (2) explore the ethical and data ...

Next-generation DNA sequencing has the potential to dramatically accelerate biological and biomedical research, by enabling the comprehensive analysis of genomes, ...

Next generation sequencing was also done on plasma cell-free DNA. All the initial diagnostic tests were found to be negative, but investigation with metagenomics showed M ycoplasma hominis .

Next-generation DNA sequencing has started a revolution in genomics and created the opportunity for large-scale sequencing projects, such as the recently announced 1,000 Genomes Project—an ...