A study led by University of Cincinnati Cancer Center researchers sheds new light on the mechanisms by which a major oncogene ...

This review summarizes current experimental and clinical evidence for the concept of oncogene addiction and describes molecular mechanisms that may explain this phenomenon. In addition ...

A study led by University of Cincinnati Cancer Center researchers sheds new light on the mechanisms by which a major oncogene ...

CNIO researchers have now discovered that this oncogene is capable of 'self-activation', by means of a previously undescribed molecular mechanism. This finding has implications for the development of ...

Citation: The first oncogene was found more than 40 years ago: Research discovers it has a previously unknown mechanism of action (2023, October 31) retrieved 23 May 2025 from https ...

The process of necrosis, a form of cell death, may represent one of the most promising ways to change the course of human ...

Experts across scientific and clinical fields, writing in Nature Oncogene, explore the emerging role of necrosis in ...

Different types of mutation, such as deletion, substitution, and insertion, can activate proto-oncogenes. Mechanism of formation cancer cells. Image Credit: Art of Science/Shutterstock.com Proto ...

Finally, as novel targeted therapies with different mechanisms of action, such as ADCs, enter the clinics, it is of interest to evaluate whether these can be used to treat and to improve outcomes of ...