The proximal tubule—part of the kidney's nephron—is a target of acute kidney injury (AKI), and its response to injury determines whether the kidney undergoes repair or progresses to chronic ...

If scientists could build a nephron, in theory they could build kidneys, but that will require developing several additional interconnected parts, which will probably take many more years.

Chronic kidney disease (CKD) is a global health threat, affecting over 10% of the world population, including an estimated 37 million Americans. Importantly, glomerular diseases account for 70% of all ...

McMahon led a team of researchers building a blueprint of how the parts fit together ... diversity of cell types in the nephron, when attempting to grow kidneys in laboratory settings, scientists ...

These findings suggested that KCTD1 plays an important function in the kidney. In the current study, Marneros reports that KCTD1 acts in a part of the nephron known as the distal nephron to ...

Oxburgh and his team are focusing on the nephrons, the parts of the kidney where waste is filtered ... In the lab, the embryonic stem cells are grown into nephron progenitor cells, which are ...

The consortium's aim is to develop a functional nephron — which is the basic structural and functional unit of the kidney — on a chip device that ... of Cambridge will develop the glomerular part of ...

This provides a detailed look at how energy is generated and used up in different parts of ... in different nephron segments under pathophysiological conditions using the kidney slice culture ...

A person’s kidneys are part of the excretory system ... This waste travels through the collecting duct of the nephron, where excess water is absorbed back into the bloodstream.

McMahon led a team of researchers building a blueprint of how the parts fit together and work ... To achieve the full diversity of cell types in the nephron, when attempting to grow kidneys in lab ...