A pioneering study has shed new light on how subcellular organelles divide and multiply. A pioneering study has shed new light on how subcellular organelles divide and multiply. The study, led by ...

The cytoplasm of eukaryotic cells is elaborately subdivided into membrane-bound compartments called organelles, each precisely tailored for a defined set of biochemical reactions. Cells must ...

Peroxisomes undergo both constitutive (independent of extracellular stimuli) division during mitosis and regulated division induced in response to some external signal. A specific subset of ...

Two mechanisms by which peroxisomes proliferate are known: division of an existing peroxisome and creation of a new one by budding from another cell organelle, the endoplasmic reticulum (ER).

In cells that were given lopsided levels of peroxisomes, cell division took longer to complete, and the architecture that separates genetic material, the mitotic spindle, was misaligned. The net ...

The work, published in Science in an article titled, “Macrophage peroxisomes guide alveolar ... of Carter Center for Immunology Research and the Division of Infectious Diseases and International ...

We found a defect of the fission of both mitochondria and peroxisomes, as well as a heterozygous, dominant-negative mutation in the dynamin-like protein 1 gene (DLP1). The DLP1 protein has ...

Peroxisomes are vital cell components that degrade cellular toxins and long-chain fatty acids. Their malfunction may result in severe, often lethal disorders. RUB researchers—Medical Faculty ...

University of Alberta researchers have found that peroxisomes are required for cells in the innate immune response to bacteria and fungi. The discovery was first made in fruit flies. Research ...

I hope our work could lead to new peroxisome-centric therapies that can help people suffering from long COVID." Jie Sun, PhD, UVA's Carter Center for Immunology Research and UVA's Division of ...

The study, led by Professor Michael Schrader from the University of Exeter, has explored on peroxisome dynamics and revealed alternative pathways for their division. Organelles are the functional ...

University of Alberta researchers have found that peroxisomes are required for cells in the innate immune response to bacteria and fungi. The discovery was first made in fruit flies. Research ...