The plague of Justinian, the Black Death, and the 500 years of plague outbreaks that followed the Black Death, were all caused by variants of the same bacterium.

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To plague aficionados, the Justinian Plague, which in the 6th century AD is thought to have killed 30 million to 50 million from Asia to Africa to Europe, is hardly a footnote.

What scientists hoped to discover in the 1,500-year-old teeth was whether the plague that killed more than 100 million during the Justinian outbreak was a strain from the Yersinia pestis bacterium ...

Bubonic plague, the disease's most common form, ... The first well-documented crisis was the Plague of Justinian, which began in 542 A.D. Named after the Byzantine emperor Justinian I, ...

The Yersinia pestis strain responsible for the Plague of Justinian between A.D. 541 and 543 was of a different lineage than the strain that caused the Black Death 800 years later, with both ...

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Historians know it as the Eastern Roman Empire’s Plague of Justinian, which spread through the Mediterranean, Europe, and the Near East in the 6th century AD.

Changes in the climate may have caused disruptions to Roman society that manifested as disease outbreaks, ... from about C.E. 215 to 266; and a pandemic that began with the Plague of Justinian, ...

The disease re-emerged in several waves over more than 500 years and persisted in that form until 1840. ... In both the Justinian plague from the 500s and the Black Death, ...

Wagner DM, Klunk J, Harbeck M, et al. Yersinia Pestis and the Plague of Justinian 541–543 AD: A Genomic Analysis. The Lancet Infectious Diseases . April 2014.