It is produced by macrophages, T cells, mast cells, endothelial cells, and fibroblasts. ACROBiosystems' human GMP GM-CSF proteins are produced and quality-controlled in a GMP-compliant facility.

The levels of the therapy in the CSF were comparable to or exceeded those in plasma, surpassing the IC 90 levels required for efficacy in cell-based assays. A-005 displayed dose-proportional ...