A dosage formula has been derived from a retrospective analysis of carboplatin pharmacokinetics in 18 patients with pretreatment glomerular filtration rates (GFR) in the range of 33 to 136 mL/min.

The final data point collected should be the drug distribution ratio of human whole blood to plasma. The equation used to establish the relationship between in vitro and in vivo clearance is ...

Fujirebio today announced that the U.S. Food and Drug Administration (FDA) has granted 510(k) clearance for the company’s ...

Within the vascular compartment these particles or molecules encounter blood cells, platelets, coagulation factors and plasma proteins ... The HD affects blood clearance and therefore blood ...

Pharmacokinetic analyses showed significant correlations between CrCl and the plasma clearance of both total topotecan [Spearman's correlation coefficient (r2) = 0.65, P = .00001] and topotecan ...