The proteins that finely control epithelial cell polarity are known as tumour suppressors or proto-oncoproteins. Loss of epithelial cell polarity — through deregulation of these proteins — is ...

Throughout the body, polarized epithelial cells are organized into sheets that line the surfaces and cavities of organs (for example, in the respiratory, urinary and digestive systems) to perform ...

Andrew T. Lombardo, PhD, assistant professor of biochemistry, has received a $1.9 million National Institutes of Health grant to study cell polarity signaling.

sheds light on the process by which epithelial cells, polarized cells that face the outside world, sort and deliver the ...

The polarity protein Par3 controls the mechanical properties of the main skin epithelial cells, called keratinocytes. It has functions that are highly conserved across species. Par3 also regulates ...

Signal transduction was strictly polarized to the serosal side of the epithelium ... extracellular CDNs can regulate the innate immune response of barrier epithelial cells lining mucosal surfaces.

Investigators have now determined that Eya1 phosphatase regulates cell polarity in lung epithelial stem cells. Investigators at The Saban Research Institute of Children's Hospital Los Angeles have ...

Throughout, the focus is on epithelial cells and how polarity mechanisms facilitate the development of their apical and basolateral surfaces, tube formation (e.g., in blood vessel development ...

The phenotypic changes typical of an epithelial-to-mesenchymal transition ... for only six months already has a loss of mesothelial-cell polarity (this sample is representative of nine samples ...

Furthermore, Map7/7D1/Ens showed planar-polarized distribution at the ovary/proximal side in epithelial cells of mouse oviducts and Drosophila pupal wings, respectively. Since the behavior and ...

Epithelial conversation An epithelial cell-coated microelectrode array with 60 precisely placed electrodes detects the minute electric signals generated when the cells are injured. (Courtesy: UMass ...

Furthermore, Map7/7D1/Ens showed planar-polarized distribution at the ovary/proximal side in epithelial cells of mouse oviducts and Drosophila pupal wings, respectively. Since the behavior and ...