The nomenclature of different promoter-associated RNA polymerase II (Pol II) species is explicitly defined in an effort to provide consistency in future literature. The known mechanistic features ...

Sharp promoters are primarily used for tissue-specific expression, whereas broad promoters are generally associated with ubiquitously ... involve hybridization of RNA or cDNA to DNA probes.

The RNA is capped at the 5’ end ... and improves its translational efficiency. The promoter sequence associated with the synthesis of rRNA is 150 base pairs in length. Two transcription factors ...

They then identified specific RNA structural characteristics that defined a subset of alternative splicing sites associated with ... SNRPA1 acts as a promoter of breast cancer metastasis." ...

This process is carried out by the enzyme RNA polymerase, which binds to specific promoter regions on the DNA and initiates ... and identifying disease-associated mutations. Despite the immense ...

The IDR in TAF2 steers the protein away from active gene promoters, where it participates ... like compartments that concentrate factors for RNA processing. Using a combination of advanced imaging ...

The second, DNA methylation, primarily involves the direct methylation of cytosine bases (5mC) in DNA by enzymes known as DNA methyltransferases, with methylation of promoter ... DNA and RNA to ...

More information: Joseph W. Wragg et al, Intra-promoter switch of transcription initiation sites in proliferation signaling-dependent RNA metabolism, Nature Structural & Molecular Biology (2023 ...

Brain tissue RNA sequencing (RNA-Seq ... pathways of target genes strongly related to the expression levels of AD-associated hub miRNAs. Pathways from the Kyoto Encyclopedia of Genes and Genomes ...