Proteins fold up into specific shapes according to the sequence of amino acids in the polymer, and the protein function is directly related to the resulting 3D structure.

Two key protein structures in the body are being visualized for the first time, thanks in part to the latest technology — ...

The amino acid sequence of a protein encodes its three-dimensional structure and determines its biological function. Although researchers can readily generate proteins with altered amino acid ...

By designing proteins de novo scientists can more efficiently create novel therapeutics tailored for specific biological ...

For most proteins, structure is function. The complex three-dimensional shapes that proteins adopt create folds and pockets that can accomplish the remarkably improbable: driving chemical ...

Understanding how they are shaped is crucial to understanding how they function ... nearly every protein in the human body, available in its AlphaFold Protein Structure Database.

In Greek mythology, Proteus, son of Poseidon and prophetic shepherd of sea-beasts, could foretell the future. The elusive sea god was difficult to capture as he assumed many forms—a lion, a serpent, ...

“Structure determines function, it’s as easy as that. If we can design proteins to look in a certain way, then they might have a certain function that could be useful,” Jon Lorsch, director ...

Although the rational protein design approach offers an increased possibility of beneficial alterations, it is not easy to accurately predict the sequence-structure-function relationship, particularly ...