Your genes are made of sequences of DNA that contain the information necessary for your cells to function and grow properly. Genes contain instructions that tell a cell to make a specific type of ...

How does a proto-oncogene cause cancer? In the early twentieth century, a tumor-causing virus called the Rous sarcoma virus (retrovirus) was discovered. 3 Host cell proto-oncogene (c-src) and Rous ...

A recent high-throughput study shows that some types of cancer are associated with mutations in a specific proto-oncogene or in a specific pair of proto-oncogenes (Thomas et al., 2007).

Translocation, point mutation, and amplification are some means by which proto-oncogenes are converted to malignant oncogenes. Studies have demonstrated that human c-sis proto-oncogene is over ...

mutagenizing proto-oncogenes into oncogenes, and as a tumor promoter, stimulating the cell to start replicating. The adaptive mtDNA mutations are milder mutations that are also seen in different ...

But mutations in specific types of genes can cause cancer. Let’s take a look at them. Proto-oncogenes help a cell grow typically. A mutation in this gene may cause it to become an oncogene.

An age-related progression from C-cell hyperplasia to medullary thyroid carcinoma is associated with various germ-line mutations in the rearranged during transfection (RET) proto-oncogene that ...

When the DNA of these gene cells mutate (change), multiple myeloma can form. Proto-oncogenes: One genetic mutation that can lead to multiple myeloma is a change in proto-oncogenes, which control ...

the analysis revealed mutations in genes for pathways related to these key oncogenes, including mutations in receptor tyrosine kinase (RTK)-RAS pathway genes, BRAF, phosphatidylinositol 3-kinase ...

Direct DNA analysis for mutations in the RET proto-oncogene can identify members of kindreds with MEN-2A, MEN-2B, or familial medullary thyroid carcinoma in whom thyroid cancer will develop.