Generalized pustular psoriasis may be caused or triggered by various factors, including genetic mutations, infections, and certain medications. Generalized pustular psoriasis (GPP) is a severe ...

Pustular psoriasis is characterized by white or yellow, pus-filled, painful pustules surrounded by red skin. The pus isn’t ...

The pustular form of psoriasis has also been linked to specific mutations in the interleukin 36 receptor antagonist IL36RN gene. Abnormal growth of skin cells or keratinocytes and immune system ...

More information: Jamie L.W. Rhoads et al, Real-world clinical characteristics and treatment patterns of generalized pustular psoriasis flares, Journal of the American Academy of Dermatology (2025 ...

Psoriasis is a disease that causes itchy, dry patches on your skin. Up to 40% of people with psoriasis have symptoms before they're 16 years old, and 10% get it before they're 10. Children can ...

German drugmaker Boehringer Ingelheim has its first regulatory approval for spesolimab, its antibody therapy for rare and life-threatening skin disorder generalised pustular psoriasis (GPP), in ...

Boehringer Ingelheim's spesolimab has shown encouraging efficacy in a phase 2 trial in generalised pustular psoriasis (GPP), a rare and life-threatening skin disorder. GPP is very different from ...

Suggested remit: To appraise the clinical and cost effectiveness of spesolimab within its marketing authorisation for treating generalised pustular psoriasis flares in adults.

IT’S not often that one sees avant-garde dresses being displayed at a medical conference, but that was certainly the case during the recent 25th World Congress of Dermatology in Singapore.

Children with inflammatory skin diseases are at an increased risk ... Patients with generalized pustular psoriasis continued to experience frequent flares that were often uncontrolled by ...

Unlike other types of psoriasis, GPP involves severe bouts of systemic (body-wide) inflammation that causes painful, sterile pustules over large areas of inflamed skin. The condition can also lead ...