What have we learned about RNA structure and function so far? Although RNA is a single-stranded molecule, researchers soon discovered that it can form double-stranded structures, which are ...

It is a polymeric molecule composed of nucleotides ... and has a single-stranded structure. Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases (Image: ...

The researchers then used cryo-EM to visualize the 3D structure of the RNA polymerase in this active, RNA-bound state at ...

However, in the half-century since the structure of DNA was first ... inhibit transcription of an mRNA molecule that has a sequence complementary to its RNA component. Inside the eukaryotic ...

This is an RNA molecule generated in the lab that the team first presented in 2023. The researchers from the Institute of Organic Chemistry were able to determine the 3D structure of SAMURI using ...

The chemical structure of uracil, showing its single-ring pyrimidine structure. Uracil forms hydrogen bonds with adenine in RNA, contributing to the molecule's structure and function. (Image: Public ...

The 3rd RNA- Targeted ... RNA targeting small molecule community to not only address key challenges of the field, such as successful determination and prediction of RNA structure and role in ...

These insights from researchers could have major implications for diseases like cancer, where gene expression goes awry.

Because RNAs are so central to our biology, they are also drivers of a wide array of diseases. Defects in how RNA is produced ...

Later it was found that the sugar in nucleic acid can be ribose or deoxyribose, giving two forms: RNA ... genetic molecule. Scientists still needed to figure out this molecule's structure to ...