As RNA-Seq is quantitative, it can be used to determine RNA expression levels more accurately than microarrays. In principle, it is possible to determine the absolute quantity of every molecule in ...

The method involves isolating and amplifying RNA from each individual cell ... Many newer techniques have expanded on the principle of scRNA-seq by combining transcriptomics with other ‘omics ...

Single-cell RNA-sequencing protocols (drop-seq and Patch-seq ... functional circuit What are unique cell types and organization principles that may have been evolved to endow the primate brain with ...

"As a proof of principle, we sequenced aged frontal cortex ... the RNA patterns in complex diseases and deep long-read RNA sequencing will be a necessary tool for that work.