Nature4h
Newfound bat virus that uses notorious receptor poses ‘spillover’ risk
The virus is related to the pathogen that causes Middle East respiratory syndrome and capitalizes on the same ‘entry receptor ...
GEN1d
AI-Guided Receptor Engineering to Improve Performance in Cell Therapies
Using protein structure prediction tools, researchers have uncovered receptor structure-function relationships to improve ...
The Scientist1d
Synthetic T Cells Provide Precision Immunosuppression
Scientists engineered T cells to protect instead of kill, potentially enabling targeted treatments for autoimmune disease and ...
EurekAlert!2d
Tweaking cancer cell response to ultrasound treatment
Tweaking the spacing between binding domains on the ECM surrounding cancer cells can boost their killing via ultrasound ...
Medscape8d
Promise for CAR T-Cell Therapies in Solid Tumors?
CAR T-cell therapies have demonstrated efficacy in treating blood cancers but, so far, their safety and effectiveness in ...
Baylor College of Medicine1d
Long-term survival following CAR T cell therapy to treat neuroblastoma
An 18-year survivor of neuroblastoma, a solid childhood tumor that develops in immature nerve cells, is believed to represent ...
Healio17h
FDA accepts IND for allogenic CAR T-cell therapy that could bypass lymphodepletion
The FDA has accepted an investigational new drug application for ALLO-329, an allogeneic chimeric antigen receptor T-cell ...