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The company’s Repatha (evolocumab) was added to optimised statin therapy in a phase 3 trial, and resulted in statistically significant regression of atherosclerosis in patients with coronary ...
The final draft guidance recommends Sanofi's Praluent (alirocumab) and Amgen's Repatha (evolocumab) for adults with primary hypercholesterolaemia or mixed dyslipidaemia to help reduce risk of ...
It’s not known whether Repatha (evolocumab) is safe to use while pregnant or breastfeeding. Certain factors may determine whether you should use the drug during this time. It’s not known ...
[Repatha package insert;9a] When PCSK9 is inactivated or inhibited, the LDL receptor/LDL cholesterol (LDL-C) particle complex is still internalized by endocytosis; however, once in the cell ...