Kanna belongs to a class of substances known as empathogenics, which primarily function by increasing the release of ...

Serotonin antagonists, specifically cyproheptadine, have been used, but the documented benefits are purely anecdotal. Serotonin syndrome, also known as serotonin toxicity, is an iatrogenic ...

Preclinical Data to Support Advancement Toward First-in-Human Clinical Trials SARASOTA, FL, March 26, 2025 (GLOBE NEWSWIRE) - ...

A study of depressed individuals found that an eight‐week treatment with selective serotonin reuptake inhibitors (SSRIs) reduced the activity of 5-HT4 receptors—a specific type of serotonin ...

However, no studies have been published so far on the effects of serotonin receptor agonists on pain perception in humans. Methods: The effects of buspirone (30 mg p.o.) on thermal sensory and ...

Lasmiditan is a promising treatment for menstrual migraine, offering sustained pain relief comparable to or exceeding that of triptans. However, further research is needed to fully assess its safety ...

Then, they evaluated whether administering serotonin or serotonin agonists would induce locusts to become gregarious, even in the absence of sensory stimuli associated with other locusts ...

A second study comparing telcagepant with rizatriptan (Maxalt; Merck) — a drug from the triptan class of serotonin receptor agonists, which are currently the standard of care for migraine ...