When people think of DNA, they usually think of genes, the parts that code for proteins and drive inherited traits. But there ...

A deeper understanding of how DNA changes over generations helps scientists learn why people differ and how diseases develop.

NIH’s SMaHT Network will chart trillions of somatic mutations to reveal how our DNA changes over a lifetime. In a nutshell ...

They want longer, more complex DNA sequences (even whole genomes), and they want high accuracy (down to a single base). But longer, more complex sequences often need to be put together from scratch.

Every living cell must interpret its genetic code—a sequence of chemical letters that governs countless cellular functions. A ...

Scientists push single-molecule DNA sequencing to the next level Two new tools created at Gladstone Institutes allow scientists to study DNA at single-molecule resolution using fewer cells than ...

PacBio describes the sequencer as an improvement over its current high-capacity Sequel IIe long-read hardware. Though both rely on what the company has dubbed HiFi sequencing, the Revio includes a ...

Antibiotics are one of the greatest triumphs in the history of medical science—but these lifesaving tools have a dark side.

Over the past decade, reads—the product of DNA sequencing—have been getting longer. Long-read sequencing has allowed scientists to sequence troublesome “dark regions” of the genome that are ...

The DNA bricks were then typeset onto the DNA template in a fixed sequence, each brick containing a single bit of information (called an epi-bit) in the form of a 0 or 1.

This method uses DNA ligases instead of DNA polymerases, which attach fluorescently tagged short sequences instead of nucleotides. Before sequencing, ... Single-cell DNA methylome sequencing of human ...

An STR is a short sequence of base-pairs on the DNA that is repeated some number of times, such as GATCGATCGATCGATC (on the complementary strand, this STR will have the sequence CTAGCTAGCTAGCTAG ...