TAS-Seq employs a nanowell/magnetic bead-based single-cell RNA sequencing platform, terminal transferase enzyme, and dideoxynucleotide phosphate terminators to generate high-precision information ...

Now, two groups performed single-cell RNA sequencing (scRNA-seq) of immune cells and combined the data with fine mapping of autoimmune disease–associated genetic variants. Together ...

Single-cell RNA-seq with spike-in cells enables accurate quantification of cell-specific drug effects in pancreatic islets. Genome Biology , 2020; 21 (1) DOI: 10.1186/s13059-020-02006-2 Cite This ...

Named Sc-SPORT for Single Cell Structure Probing Of RNA Transcripts, this new approach is able to identify biomarkers crucial for human development and disease, based on shape rather than sequence ...

Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not ...

More information: Zhonghua Tong et al, Single-Cell RNA Sequencing Maps Immune Cell Heterogeneity in Mice with Allogeneic Cardiac Transplantation, Cardiovascular Innovations and Applications (2023 ...

In contrast, single cell sequencing allows DNA or RNA from individual cells to be amplified and sequenced, capturing each cell’s uniqueness. 2 Scientists often use single cell sequencing to detect ...

Through single-cell RNA sequencing, a research group has successfully illuminated the characteristics of Myeloid immune cells in coronary plaque, which causes acute coronary syndrome (this term ...

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This study represents the largest single-cell RNA sequencing cohort of gastric adenocarcinoma to date and brings important new insights into how these cell populations impact disease progression." ...