Tumors are complex systems characterized by variations across genetic, transcriptomic, phenotypic, and microenvironmental ...

Eight years ago, 10x Genomics launched the first commercially available single-cell RNA sequencing (scRNA-seq) product for the company’s flagship instrument, the 10x Chromium. (This occurred one ...

Named Sc-SPORT for Single Cell Structure Probing Of RNA Transcripts, this new approach is able to identify biomarkers crucial for human development and disease, based on shape rather than sequence ...

A new method combines microscopy with single-cell RNA analysis to make the technique more accessible and scalable, giving researchers an advantage in the numbers game of single-cell analysis.

a technique for rapidly sequencing RNA from single cells. This advance should enable scientists to learn more about the critical genes expressed in each cell, and to discover subtle differences ...

Scientists at St. Jude Children's Research Hospital, the National Center for Genomic Analysis and the University of Adelaide ...

The transcriptome is the complete set of these RNA sequences within a given cell. Among scientists, single-cell analysis is frequently compared to a fruit smoothie, Lee notes. Many types of ...

they drew out their idea for how to increase the scalablility of single-cell RNA sequencing (scRNA-seq) on a whiteboard. At that time, roughly five years ago, “large scale was about 100 cells ...

Single-cell RNA sequencing (scRNA-seq) is one of the most important methods to study biological function in cells, but it is limited by potential inaccuracies in the data it generates. Now ...

In contrast, single cell sequencing allows DNA or RNA from individual cells to be amplified and sequenced, capturing each cell’s uniqueness. 2 Scientists often use single cell sequencing to detect ...