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It can also create a few other types of RNA, including small nuclear RNA (which forms complexes with other proteins to process mRNA) and microRNA ... This image was created by reconstructing X-ray ...

No large RNA structure database exists that correlates sequence with 3D topology. Successful protein-centric methods like ...

Scientists report their discoveries of a previously unknown mechanism in the nucleus that processes non-coding RNA molecules to generate what might be a new class of small RNAs.

“We discovered around 2,000 new RNA structures that are able to bind drug-like small molecules, and identified six new chemotypes able to bind RNA,” said Matthew D. Disney, PhD, chemist and ...

Dublin, May 29, 2025 (GLOBE NEWSWIRE) -- The "RNA Targeting Small Molecule Drug Discovery Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2020-2030F" has been added to ...

Nanotechnology enables visualization of RNA structures at near-atomic resolution Date: May 2, 2022 Source: Wyss Institute for Biologically Inspired Engineering at Harvard ...

Small nuclear RNA, or snRNA, teams up with a host of proteins to form the spliceosome, a complex that snips out extraneous segments of mRNA to make a fully functional molecule that can then code ...

The discovery hinges on a small molecule that latches onto and inhibits a structure in the SARS-CoV-2 RNA genome, preventing the virus from pumping out the proteins it uses to replicate and infect ...

Unlike the RNA-binding proteins FUS and TDP43, NONO and SFPQ aggregated in nuclei in the A53T neurons. Ditto in cortical tissue from four people who had had DLB (image below). Each had an average of ...

Combination of nucleic acid nanotechnology and cryo-EM gives unprecedented insights into the structures of large and small RNAs, advancing RNA biology and drug design Peer-Reviewed Publication ...