The phase 3 SURPASS-4 trial published in 2021 established that tirzepatide lowers blood sugar and supports weight loss better than insulin glargine (a long-acting insulin) for type 2 diabetes (T2D).

"Results from SURPASS-SWITCH suggest that escalating dulaglutide is not as effective in reducing HbA1c and may further delay diabetes control than switching to tirzepatide," they wrote.

For example, analysis of data from the SURPASS-3 trial by Viljoen et al. revealed that the median time to first achieve the HbA1c of 7.0% was 8.1 weeks for each dose of tirzepatide compared with ...

The reason for this is unclear. More information on the cardiovascular effects of tirzepatide will come with the results of the SURPASS-CVOT, due to be completed later in 2025, Billings and ...

Patients on GLP-1 medications lost about half as much weight as participants did in clinical trials, NYU researchers found.

A recent analysis of the SURPASS-3 trial unravels the impact of treatment with the drug tirzepatide on muscle volume and fat infiltration in individuals with type 2 diabetes. Published in The ...

That trial, called SURPASS-CVOT, will finish in mid-2025 and could “really give us the details we need to see how effective tirzepatide is in reducing heart disease,” he says. Even if ...

The present review explores the in vitro and in vivo benefits of Tirzepatide's effects, with notes on the drug's pleiotropic effects on other organs. It focuses on the SURPASS and SURMOUNT ...

Researchers compared the safety and efficacy of tirzepatide (brand name Zepbound) and semaglutide (brand name Wegovy) in a 72-week clinical trial. The randomized, controlled trial — called ...

(RTTNews) - Eli Lilly and Company (LLY) Thursday announced positive topline results from the SUMMIT phase 3 study evaluating tirzepatide in adults with heart failure having preserved ejection ...

The SURPASS-CVOT trial will help researchers learn more, Sattar said. The cardiovascular outcomes trial is testing tirzepatide against the incretin mimetic dulaglutide (Trulicity; Eli Lilly), a drug ...