Smad2 and Smad3 are highly homologous members of the receptor-regulated subfamily of Smad proteins with a central role in TGF-β signalling and target gene regulation. In conclusion, using a high ...

and suppressing the integrin β1/transforming growth factor-beta (TGFβ) signaling pathway. A new study by researchers from Harbin Medical University, in China, provides insights into the ...

These proteins interact with critical signaling pathways, such as PI3K/Akt, Wnt/β-catenin, and TGF-β/Smad, influencing cell proliferation, migration, and apoptosis. In glioblastoma, for instance ...