Four years ago, Cheng and co-senior author Stephen Nishimura, MD, discovered that TGF-Beta could signal to a receptor even when bound within its straitjacket, whose scientific name is latency ...

Transforming growth factor-beta (TGF-β), a well-known morphogen ... The ligand DAF-7, secreted from ASI neurons, acts on its ...

This presentation will highlight a preclinical dataset that provides insights into the role of inhibiting TGF-β in overcoming acquired KRAS-G12C-inhibitor drug-resistant KRAS-G12C-mutated lung cancer.