To produce cannabinoids in yeast (Saccharomyces cerevisiae), UC Berkeley synthetic biologists first engineered yeast's native mevalonate pathway to provide a high flux of geranyl pyrophosphate ...

A biosynthetic approach to produce this form of cannabinoid analog was devised by the team; this exploited the promiscuity of yeast metabolic pathways and the nature of the fatty acid precursors.

To accomplish this, we engineered the native mevalonate pathway to provide a high flux of geranyl pyrophosphate and introduced a heterologous, multi-organism-derived hexanoyl-CoA biosynthetic pathway.

Xinteza API Ltd., a biosynthesis technology company, revealed the discovery of a new catalytic enzyme, capable of solving one of the major bottlenecks that has so far limited the design of ...

2-aminoadenine biosynthesis pathway elucidated Since it was discovered in 1977, cyanophage S-2L has been the only known exception, and the biosynthesis pathway of 2-aminoadenine has remained unknown.