Sodium phosphate is an umbrella term that refers to multiple combinations of sodium (salt) and phosphate (an inorganic, salt-forming chemical).

Chicago, IL - Results of two trials of tolvaptan (Otsuka America Pharmaceutical), a novel oral vasopressin V2-receptor antagonist, show that treatment effectively increased serum sodium ...

Tolvaptan, an arginine vasopressin receptor antagonist, decreases urinary supersaturation in kidney stone formers by considerably increasing diuresis, suggesting that this drug might be an ...

The tolvaptan treatment effect did not differ significantly between calcium oxalate and calcium phosphate stone types. Serum sodium increased slightly while on tolvaptan.

On days 4 and 30 in both studies, more tolvaptan-treated patients than placebo recipients had normal serum sodium concentrations, and marked hyponatremia was more common in placebo recipients.

An advisory committee to the FDA voted not to recommend tolvaptan for the indication of slowing kidney disease in adults at risk for rapidly progressing autosomal dominant polycystic kidney disease.

Once-daily dosing with Otsuka's investigational oral medication tolvaptan, a vasopressin receptor antagonist, was associated with improvements in signs and symptoms of acutely decompensated heart ...

Trisodium phosphate is a common and safe additive used in small amounts in various foods, not a form of "paint thinner".

Results of the two largest studies on hyponatremia found that the investigational drug tolvaptan treated hyponatremia -- water intoxication -- more effectively than available treatments. These ...

Lupin gains US FDA approval for Tolvaptan tablets in various dosages, marking a significant entry into the nephrology market. The tablets, bioequivalent to Otsuka's Jynarque, will be manufactured ...

The FDA has issued a drug safety communication concerning tolvaptan (Samsca, Otsuka), a selective vasopression V2-receptor antagonist used in heart failure patients to treat clinically significant ...

Lupin shares gain on tentative USFDA nod for Tolvaptan tablets This product will be manufactured at Lupin’s Nagpur facility in India.