"Comparisons of our findings with other alternative toxicology animal models, namely zebrafish larvae and nematodes, demonstrated that planarians are comparably sensitive to the tested chemicals ...

Organ-on-a-chip microdevices can be more capable than cell culture models and provide economical alternatives to animal and clinical studies for drug screening and toxicology applications.

Rethinking animal models. ... Ewart L, Apostolou A, Briggs SA, et al. Qualifying a human Liver-Chip for predictive toxicology: Performance assessment and economic implications. bioRxiv.

Predictive Toxicology: Organ-Chips Demonstrate Superior Performance to Animal Models and Spheroids. Webinar . ... Why preclinical models with greater predictive validity will improve clinical success ...

Almost 40 years later, what are some of these alternatives, and how much progress have we made? Before we delve into the answer, there's one important distinction to make: although "animal testing ...

VivoSim Labs has launched non-animal toxicology models to enhance drug development, aligning with FDA's initiative to phase out animal testing. Quiver AI Summary.

Charles River to develop animal-free inhalation toxicology tests. To that end, the Pistoia Alliance in March launched a project called the Non-Animal Models Community, ...

Researchers examine how the use of animal testing to identify endocrine-disrupting substances in the EU can be reduced.

Outside of medical products designed for humans, non-animal models can also support innovation in veterinary and agricultural medicines, cosmetic testing and eco-toxicology. Non-animal models can ...

Animal models have played a critical role in bringing new therapies to market, but testing compounds on animals raises ethical concerns. In addition, animal models don’t always predict toxicity ...

Charles River Laboratories has launched a new program to come up with an animal-free alternative to inhalation toxicology tests, marking another move in its larger plan to reduce reliance on ...