Brain metastases from prostate cancer (PC) seem to be more frequent than in the past, possibly because advances in the treatment of patients with castration-resistant PC have prolonged their survival.

the above findings suggest that tumor stroma is far from a passive bystander during tumor metastases. Tumor cells influence stromal changes including remodeling of the ECM, and this changed stroma ...

Metastasis causes >90% of cancer death. The emergence, persistence, therapy resistance and lethality of metastatic cancer is driven by dynamic and tenacious metastasis stem cells (MetScs). The Ganesh ...