The dengue virus has a roughly spherical shape. Inside the virus is the nucleocapsid, which is made of the viral genome and C proteins. The nucleocapsid is surrounded by a membrane called the ...

Research interests: assembly and structure determination of viruses, virus-receptor interaction, antivirals, neutralizing antibodies, electron cryo-microscopy, image processing, crystallography. Sarah ...

Scientists at Purdue University and the University of Minnesota have solved the three-dimensional structure of the central component of a biological "motor" that powers the DNA packaging system in a ...

The measles virus is an enveloped virus bearing a lipid bilayer. The bilayer holds the receptor binding hemagglutinin (H) protein and the fusion (F) protein. For infection to happen, the H protein ...

A major challenge lies in the virus's structure and regulatory mechanisms, which have remained largely unclear. In particular, scientists have long struggled to fully understand its nucleocapsid ...