The alkanes are a homologous series with a structure based on a carbon chain - each carbon atom forms four covalent bonds The intermolecular forces vary between molecules, so different organic ...

Prior to 2000, many drugs that formed a covalent bond with targets did so non-selectively, which often led to undesired side effects when compared to non-covalent drugs. This led to the belief that ...

Chinese scientists proposed a novel imine-to-olefin transformation strategy to synthesize single-crystal sp² carbon-linked covalent organic frameworks (sp²c-COFs). COFs are crystalline, porous ...

Covalent drugs function by forming covalent bonds with specific amino acid residues, enabling sustained modulation of target proteins. Compared with cysteine-targeting strategies, lysine serves as ...