An antibody discovery platform revealed more than 60 monoclonal antibodies specific to patients with alpha-gal syndrome, ...

This is thanks to advances in bulk and single-cell RNA-sequencing (RNA-seq) technologies that can capture every RNA molecule expressed in a cell: its transcriptome. The computational methods ...

Researchers mapped HIV-1’s translation strategy, revealing RNA elements like uORFs, iORFs and an intricate frameshift site structure that regulate viral protein synthesis. These findings highlight ...

Spatial transcriptomics is a cutting-edge technique that characterizes gene expression within sections of tissue, such as ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

Scientists are devising new ways to overcome this obstacle for RNA sequencing. RNA is more subject to degradation than DNA, whether chemical, physical, or enzymatic. Complicating the matter, ...

What's the difference between mRNA and pre-mRNA? It's all about splicing of introns. See how one RNA sequence can exist in nearly 40,000 different forms. Next, the snRNPs U2 and U4/U6 appear to ...

RNA polymerase is an enzyme that is responsible for copying a DNA sequence into an RNA sequence, duyring the process of transcription. As complex molecule composed of protein subunits, RNA ...

RNA-based diagnostic tools, such as RT-PCR and RNA sequencing, are widely used for detecting and quantifying RNA in biological samples. These techniques are invaluable for diagnosing viral infections, ...

Researchers developed pig retinal organoids similar to human ones, advancing stem cell-based vision restoration and enabling ...

for example—is translated using self-folding RNA alone. First, a DNA sequence is designed in a computer-assisted process. It ...