A process using human stem cells can generate the cells that cover the external surface of a human heart — epicardium cells — according to a multidisciplinary team of researchers. "In 2012, we ...

The group's method of generating epicardium cells could be useful in clinical applications, for patients who suffer a heart attack. According to the Centers for Disease Control and Prevention, ...

Medical researchers have found that a key to the zebrafish's ability to regenerate cardiac tissue lies in the outer layer of the heart known as the epicardium. When this critical layer is damaged ...

Embryonic epicardium is crucial for normal heart morphogenesis. The tissue originates from the proepicardial organ, with cells migrating to form the outer mesothelial layer, giving rise to non-myocyte ...

Thanks to a thin layer of tissue that covers the heart called the epicardium, zebrafish are able to regrow damaged cardiac tissue. New research has shown that the epicardium is able to heal not ...

Meanwhile, developmental genes in the epicardium--a cell layer that surrounds the entire heart and influences embryonic heart development--switch on, activating the epicardial cells.

Using immunofluorescence techniques, they also demonstrated that oxytocin moved down to the epicardium, bound to oxytocin receptors, and triggered surrounding cells to transition into EpiPCs. These ...

Researchers show for the first time that the neurohormone oxytocin has a previously unsuspected function in both zebrafish and human cell cultures: it stimulates mature cells in the epicardium of ...