Collecting duct carcinoma (CDC) is a rare and aggressive form of kidney cancer. It develops in the Bellini duct, or the collecting duct, of the kidneys. It may cause no symptoms until it is in an ...

Collecting duct carcinoma of the kidney is histologically characterized by tubulopapillary pattern of growth, marked desmoplasia, inflammatory infiltrate, high-grade cytological features with ...

PKD1-Dependent Renal Cystogenesis in Human Induced Pluripotent Stem Cell-Derived Ureteric Bud/Collecting Duct Organoids. Journal of the American Society of Nephrology, 2020; ...

There are different types of kidney cancers, including renal cell carcinoma, transitional cell cancer, Wilms’ tumor, renal medullary cancer, and collecting duct tumors.

Collecting ducts derived from iPS cells with the heterozygous PKD1 gene mutation, as well as those derived from patient iPS cells, formed cysts, although partially. view more .

Joint research, led by Kumamoto University in Japan, has successfully reproduced the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) from human iPS cells in vitro.

image: Cross-sections of two collecting ducts are shown. Tissue proteins are colored with fluorescent dyes: aquaporin 2 (red), F-actin (yellow), tight junction protein 1 (green) and cell nuclei ...

Background: Collecting duct carcinoma (CDC) is a rare type of non-clear cell renal cell carcinoma with an aggressive course and poor prognosis. The treatment of metastatic disease remains ...

A team led by experts at Cincinnati Children’s has developed the first advanced kidney organoid that can fuse blood-filtering nephrons to waste-removing collection ducts. Details were published ...