Epithelial and endothelial cells expressing the primary Coxsackie virus B adenovirus (Ad) receptor (CAR) and integrin coreceptors are natural targets of human Ad infections. The fiber knob of ...

Nature Reviews Molecular Cell Biology - Integrin activation comprises initial and intermediate signalling events and, finally, the interaction of integrins with cytoplasmic regulators such as ...

Nascent Integrin Adhesions Form on All Matrix Rigidities after Integrin Activation. Developmental Cell , 2015; 35 (5): 614 DOI: 10.1016/j.devcel.2015.11.001 Cite This Page : ...

Sigvotatug Vedotin is an ADC that targets integrin αvβ6-positive tumor cells. It has an engineered antibody that ensures high ...

Talin binds to integrin via its "head" and connects it to the cytoskeleton, thereby acting as a part of the cellular mechano-signalling network, which affects cell adhesion, migration, but also ...

Their roles in controlling cell behavior, coupled with their cell-surface location, have made them highly attractive drug targets. But while researchers have made significant progress tracing integrin ...

Immune-cell integrins are excellent models for studying integrin activation. They are normally inactive, which allows the cells to circulate freely in the bloodstream.

The pattern of integrin distribution is closely matched to the pattern of attack of the SARS-CoV-2, with integrin b1 involved in the functioning of type 2 alveolar epithelial cells.

Cancer cell movement during metastasis is a dynamic process regulated by several different signals. However, the way cells receive, process and respond to these signals has been extremely hard to ...

Conclusions: We found a shift in the abundance of immune cells in the ccRCC TIME following IO treatment. Additionally, we saw significant autocorrelation of two transcripts associated with the EMT ...