Scanning electron microscopy images of the cuticle (skin) of C. elegans kept at 25 degrees Celsius show wrinkles on an old (9-day old) adult wild-type worm (left) but smooth skin on an npr-8 ...

The analysis of wild-type C. elegans and 9 mutant strains revealed that sulforaphane inhibited DAF-2 insulin/insulin receptor signaling and thereby increased DAF-16 nuclear translocation ...

To lay the groundwork for a detailed analysis of cellular changes that comprise ageing in C. elegans, we first examined the appearance of wild-type animals over time using Nomarski differential ...

Word of a curious worm phenomenon has spread among scientists over the years. Words like, “they’re living in giant towers, ...

In 1963, on a hunch, a South African biologist named Sydney Brenner decided to study a species of worms named C. elegans. The worms turned out to be the perfect lab animal. They were simple ...

This valuable study concerns a model for transgenerational epigenetic inheritance, the learned avoidance by C. elegans of the PA14 pathogenic strain of Pseudomonas aeruginosa. A recent study ...

They then tested the drug on C. elegans and found that it increased wild-type worm lifespan. Additionally, they found that metolazone did not extend lifespans in worms in whom the genes atfs-1, ubl-5, ...

In the roundworm C. elegans, the utilization of lipids ... DAF-2 and INS-7 colocalized on the ASI neuronal surface in wild-type worms, thus indicating that INS-7 may differentially regulate ...