"The zebrafish are transparent at their larval ... If I didn't, the treatment had enabled the liver to excrete it into the fish culture medium." When the researchers tested chlorcyclizine in ...

The zebrafish is a good research stand-in for its fellow vertebrate, the human, because the two have many parts in common: brain, heart, liver, kidneys. And genome sequencing has shown that 84 ...

A new fully automated in vivo screening system (AISS) has been developed to transform drug evaluation by enabling rapid, ...

Preclinical drug evaluation, especially for cardiotoxicity, is a critical stage in the drug development process.

As a vertebrate, the zebrafish possesses many genes that perform the same or similar functions in mammals and therefore also in humans. Approximately 70 percent of zebrafish genes are also present in ...

Wee’s team found that different neurons are activated when hungry zebrafish were consuming large ... various organs — such as the gut, the liver and the pancreas — to the brain,” she ...

Zebrafish are unassuming and undemanding. Almost every child knows that – at least any child that has kept fish in an aquarium. Since the beginning of the 20th century, these fish have been one of the ...

A new fully automated in vivo screening system (AISS) has been developed to transform drug evaluation by enabling rapid, precise, and non-invasive ...

The preclinical evaluation of drug-induced cardiotoxicity is an important stage in the drug development process; however, traditional methods for screening drug candidates, such as cardiomyocyte-based ...

Using a unique, zebrafish-based phenotypic screening platform ... Era-379’s target is an undisclosed novel protein that drives peripheral liver–brain signaling and acts in concert with ...