How c-Myc regulates cell invasion is poorly understood. ... CA, USA). Mouse anti-c-Myc antibody (9E10 clone) was obtained from Santa Cruz Biotechnologies (Santa Cruz, CA, USA).

Furthermore, β1 integrin function-blocking antibodies prevent the adhesion-dependent induction of c-Myc. Adhesion of A1N4 cells results in the activation both of c-Src and of the Erk 1/2 mitogen ...