Either way, we’ll likely hear their names often on Monday Night Football, as one of those newcomers will be protecting 49ers’ quarterback Brock Purdy’s blindside against the Lions.

(Ray Chavez/Bay Area News Group) The San Francisco 49ers are tackling the Detroit Lions at home at 5:15 p.m. PDT on Dec. 30 at Levi’s Stadium on Monday Night Football. Related Articles San ...

The Detroit Lions (13-2) will visit the San Francisco 49ers (6-9) in an NFC showdown on Monday Night Football to conclude the Week 17 NFL schedule. The Lions are fighting to lock down the No. 1 ...

The NFL Week 17 schedule ends with a rematch of the 2023 NFC Championship game when the Detroit Lions travel to the West Coast to visit the San Francisco 49ers on Monday Night Football. The 49ers ...

The San Francisco 49ers take on the Detroit Lions on "Monday Night Football" in Week 17 of the 2024 NFL season. San Francisco 49ers Head coach Kyle Shanahan provided updates on LB Dre Greenlaw's ...

The Detroit Lions meet the San Francisco 49ers on Monday Night Football at Levi's Stadium in Santa Clara, California to finish Week 17 of the 2024 NFL season. The Lions (13-2) will be playing ...

The 49ers are riding a tow game losing streak into Week 17. They are poised to increase it to three in their matchup with the Lions. Here are three reasons why the 49ers will lose to the Lions.

The Detroit Lions and San Francisco 49ers met 11 months ago at Levi's Stadium with a trip to the Super Bowl on the line. San Francisco used a furious second half comeback to steal the NFC ...

Because of multiple layers of history — the 49ers offense being robust, and Jennings reliability to produce when one of the top two San Francisco receivers are out or down — we jumped on the ...

The San Francisco 49ers are prepping for Week 17 against the Detroit Lions on Monday Night Football. What they're not prepping for is a playoff push in January. At 6-9, Kyle Shanahan and the 49ers ...

The 49ers will have running back Isaac Guerendo for Monday Night Football. Guerendo, who missed last week’s game with a hamstring injury, does not have an injury designation for the game against the ...