Jared Goff and the Detroit Lions visit Levi’s Stadium for the final home game of this injury-riddled 49ers season Click to share on Facebook (Opens in new window) Click to share on Twitter ...

Either way, we’ll likely hear their names often on Monday Night Football, as one of those newcomers will be protecting 49ers’ quarterback Brock Purdy’s blindside against the Lions.

Another San Francisco 49ers starting offensive lineman is missing from practice. Starting right tackle Colton McKivitz did not participate in Friday's session. McKivitz was a limited participant ...

The Detroit Lions and San Francisco 49ers met 11 months ago at Levi's Stadium with a trip to the Super Bowl on the line. San Francisco used a furious second half comeback to steal the NFC ...

The injury report for the Detroit Lions (13-2) heading into their matchup versus the San Francisco 49ers (6-9) has five players. The 49ers (6-9) currently have 15 players listed on this week's ...

The San Francisco 49ers are prepping for Week 17 against the Detroit Lions on Monday Night Football. What they're not prepping for is a playoff push in January. At 6-9, Kyle Shanahan and the 49ers ...

There doesn't seem to be any question about quarterback Brock Purdy's future with the San Francisco 49ers. All indicators are the team is happy with his development and that his contract extension ...

San Francisco 49ers offensive tackle Trent Williams is largely considered one of the greatest to ever play the position. With 11 Pro Bowls and four All-Pro teams under his belt, Williams has been ...

SANTA CLARA, Calif. -- After missing last week because of a hamstring injury, San Francisco 49ers running back Isaac Guerendo is set to play Monday night against the Detroit Lions. Guerendo ...

Jared Goff and the favored Lions are the pick against the 49ers, The Post's Dylan Svoboda predicts. Junfu Han / USA TODAY NETWORK via Imagn Images Gambling content 21+. The New York Post may ...