Brexpiprazole's indication for the treatment of schizophrenia in adults is extended to include adolescents aged 13 years and older<su ...

The drug is a long-acting and potent serotonin 5-HT1A receptor agonist and will be added to DSP’s psychiatry and neurology research pipeline. Paul Workman, chief executive of The Institute of ...

Furthermore, 5-HT1A receptor knockout mice demonstrated an increase in anxiety-like behavior. These findings implicate the possibility of alpha-GPC in improving motivation and anxiety in humans.

Solriamfetol is Axsome’s dopamine and norepinephrine reuptake inhibitor (DNRI), TAAR1 agonist, and 5-HT1A agonist being developed for the treatment of attention deficit hyperactivity disorder ...

Cooperative regulation of anxiety and panic-related defensive behaviors in the rat periaqueductal grey matter by 5-HT1A and μ-receptors. Further evidence for involvement of the dorsal hippocampus ...

CBD enhances 5-HT1a receptor activity and glycine receptors (α3 and α1), while influencing intracellular calcium dynamics. Notably, CBD's lipophilic properties allow it to access intracellular sites, ...

It's believed that CBD works on a specific serotonin receptor in the brain, 5-HT1A [1]. This so-called serotonin signaling encourages the brain to utilize the serotonin available, resulting in a more ...

Total 4Q and full year 2024 net product revenue of $118.8 million and $385.7 million, respectively, representing 66% and 88% year-over-year growth Auvelity® 4Q and full year 2024 net product ...