The aortic segments studied above were then embedded in paraffin on end and cross-sectioned at 4 µm for subsequent immunohistochemistry, in situ hybridization, and histological evaluation.

In diabetes, hyperglycemia drives nonenzymatic glycation and oxidation of proteins and lipids, enhancing irreversible formation of advanced glycation ... 7,8) in cells of the vessel wall perturbs ...

This process leads to the formation of harmful compounds known as advanced glycation end products (AGEs ... and damage to cells. These processes are linked to chronic conditions such as heart ...

In addition to heparin/heparan sulfates, HMGB1 binds to the immunoglobulin superfamily protein RAGE (receptor for advanced glycation end-products), which mediates ... superfamilies of cell surface ...

Such oil-fried food promotes free radicals, which damage other molecules in your cells. French fries are an AGE (advanced glycation end products) food that can wreak havoc on the body. Caffeine ...