Adrenaline would presumably activate β–adrenergic receptors on the soma, which would shift the spike threshold to a higher voltage by suppressing I Ca,T and increase the firing frequency in ...

G protein-coupled receptors articles from across Nature Portfolio G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand ...

This review addresses open questions about the role of β-adrenergic receptors in cardiac function and failure. Cardiomyocytes express all three β-adrenergic receptor subtypes—β1, β2, and, at least in ...

Objectives We aimed to synthesise the available data for the effect of stopping alpha-blocker therapy among men with lower urinary tract symptoms. The focus was on symptom, uroflowmetry and quality of ...