Two recent studies from Dr. Sita Kugel’s lab at Fred Hutch Cancer Center identify a key biological signature that not only ...

Researchers have pinpointed the precise pathway in the brain that suppresses pain in times of threatening situations.

Cedars-Sinai has created a lifelike model of the mysterious and fatal disease that could help identify a cause of the illness ...

R136S, or the “Christchurch mutation,” appears to protect against Alzheimer’s disease by suppressing inflammatory signaling ...

A recent research finding adds to evidence that brain inflammation is a major driver of neurodegenerative disorders such as ...

Human exposure to toxic particles drives various diseases. Examples include gout, an acute arthritis driven by monosodium ...

Announcing a new article publication for BIO Integration journal. Liver fibrosis is caused by excessive extracellular matrix ...

Investigating tirzepatide's role in Alzheimer's reveals its potential to improve brain function and reduce inflammation, ...

FUKUOKA—Testosterone, a sex hormone produced primarily in male testes, could be the reason why men are less likely than women ...

In summary, the PD-1 signaling pathway plays an essential regulatory role in immunosuppression in sepsis by affecting immune cell function. Immunomodulatory therapies targeting the PD-1 pathway in ...

The cyclic GMP-AMP synthase (cGAS)/stimulator of interferon gene (STING) pathway can respond to double-stranded DNA (dsDNA) to mediate innate immunity. However, activation of the cGAS/STING pathway ...