New monoclonal antibodies or fusion proteins that specifically target B-cell survival or proliferation are, however, now becoming available. BCMA Stimulates plasma cell survival and IgM production ...

People commonly refer to these as B cells and T cells. The job of T cells is to help the body kill cancer cells and control the immune response to foreign substances. They do this by destroying ...

a transcription factor necessary for the transient expansion of B cells preceding plasma cell differentiation, via coupling its translation to its decay.

Last November, results from the MITIGATE trial made headlines at ACR Convergence 2024 with positive phase 3 trial data for inebilizumab, an IgG1 monoclonal antibody targeting CD19, in patients with ...

B-cell acute lymphoblastic leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most ...

Plasma cell leukemia (PCL) is a rare disease that may present de novoor secondary to plasma cell myeloma. Advanced disease and extramedullary involvement are common clinical features at presentation.