Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate cancer, as previously thought, suggests the first study of its ...

Among patients with early-stage triple-negative breast cancer, a beneficial pathologic complete response rate was higher in patients with BRCA1/2 mutations. Among patients with early-stage ...

Many mutations, such as those found in the well-known BRCA1 and BRCA2 genes, are passed down in what’s called an autosomal dominant pattern. This means that inheriting one bad gene from one ...

We've identified the following companies as similar to null because they operate in a related industry or sector. We also considered size, growth, and various financial metrics to narrow down the list ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The prevailing view on post-translational ...

JACKSON, Miss. (WJTV) – Officials with the Mississippi Department of Public Safety (DPS) said technical issues are causing delays at Driver Service Bureau (DSB) locations statewide. According to ...

Connecting decision makers to a dynamic network of information, people and ideas, Bloomberg quickly and accurately delivers business and financial information, news and insight around the world ...

The exact cause or causes of triple-negative breast cancer are unknown, but researchers have linked it to mutations in the BRCA1 and BRCA2 genes. They also have been able to identify certain risk ...

Recently, we proposed a new methodology for evaluating the repair efficiency of DNA double-strand breaks (DSB) using a model system. The model system can trace the fate of a single DSB, which is ...

Figure 1. A brief mechanism diagram of the formation process of R-loop and DSB process, which contribute to the cell genomic instability and cancer cell formation. Maintaining a balanced level of ...