A new AI tool, AAnet, has discovered five distinct cell types within tumors, offering a deeper look into cancer's inner ...

Cell subsets co-occurred in three distinct lymphoma microenvironment archetype profiles characterized by: sparsity of T cells with high frequencies of cancer-associated fibroblasts and tumor ...

As brain tumors grow, they must do one of two things: push against the brain or use finger-like extensions to invade and ...

A new study shows that cells in atherosclerotic blood vessels grow in a way that resembles tumor development. This finding ...

As the study noted, the introduction of CAR T-cell therapy as a second-line therapy in DLBCL “has significantly improved outcomes and leads to durable responses beyond 2 years in > 40% of patients.

This is a useful study in the role of CHI3L1 in Kupffer cells, the macrophages of the liver, showing that CHI3L1 alters glucose regulation in obesity. Specifically, Chi3l1 protects glucose-dependent ...

The rapid development of single-cell technology has opened up a whole new perspective for identifying cell types in multicellular organisms and understanding the relationships between them.

1 Department of Surgery, Russian Medical Academy of Postgraduate Education, Moscow, Russia 2 Department of Oncology, S.P. Botkin Clinical Hospital, Moscow, Russia Basal cell carcinoma (BCC) is a ...

Single-cell RNA sequencing can define the testicular transcriptomes at the single-cell level, while also describing the degree of cellular heterogeneity and the presence of rare subpopulations (Suzuki ...

Motivated by the objective to efficiently associate survival risk directly with cellular subpopulations extracted from scRNA-seq data, we introduce SCellBOW (single-cell bag-of-words), a Doc2vec 20 ...