Compromised antigen presentation ranks among the top mechanisms that render cancers non-immunogenic (non-responsive to immune ...

S, Principal Investigator at A*STAR SRL are co-authors of the study. While the current study focuses on basal cell carcinoma (BCC), researchers believe the technology could also be adapted to ...

CX-4945 Monotherapy: Progression-free survival (PFS) exceeded 21 months in two patients. Optimal Treatment Response: Three patients achieved partial response (PR), while ten patients had stable ...

However, how spindle tethering complexes read the cell polarity axis and how spindle attachment is coupled to mitotic progression remains poorly understood. We explore these questions in Drosophila ...

At the heart of GaN’s potential lies its crystal polarity. While both nitrogen-polar (N-polar) and gallium-polar (Ga-polar) GaN exist, N-polar variants demonstrate superior performance.

“I’ll ask if someone has ever had skin cancer, and they will tell me, ‘No, just a basal cell.’” Basal and squamous cell carcinomas are the most common types of skin cancer; more than 3 ...

Nkarta is laying off a third of its workforce, and more than half its executive team, in a bid to survive long enough to see if an experimental cell therapy it’s developing will show promise against ...

The leading eye-care company Alcon on Wednesday said it has acquired a majority stake in Aurion Biotech, capping months of legal wrangling over the future of the cell therapy developer. As part of the ...

The cells in the white dashed box on the 2nd have not yet completed the process of cell directed migration: the Golgi is relatively dispersed and has lost its polarity. At this point the localization ...

Organelle position is controlled by self-organizing cell polarity systems that orientate the cytoskeleton, which in turn move organelles to defined positions. Organelle shape, for membrane-bound ...