This important study utilizes humanized mice, in which human immune cells are introduced into immune-deficient mice, to provide convincing evidence that two helper CD4 T-cell subsets, T-follicular ...

The chemokine receptors CCR5 and CXCR4 are the two major coreceptors for HIV entry. Numerous efforts have been made to develop a new class of anti-HIV agents that target these coreceptors as an ...

Stay informed in an emergency, set your local ABC radio station in the ABC listen app, and find the frequency on your battery-powered radio. Making sense of emergency warnings It doesn't matter ...

Today, shares of CytoDyn Inc. (OTCQB: CYDY) are on a tear as the biotechnology company developing leronlimab, a CCR5 antagonist with the potential for multiple therapeutic indications, announced ...

This study is important, and the findings add substantially to the evidence base regarding CCR5 antagonist drugs for neuroprotection and stroke management. The authors adhered to the expected ...

To investigate the interaction between macrophages and neutrophils, we performed immunofluorescence staining to label macrophages (F4/80), neutrophils (MPO), and neutrophil signaling receptors (CCR2 ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Concurrent analysis of whole-genome DNA ...

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

Credit: MPE “If you look at the distribution of the galaxy clusters in the sky in a spherical shell with a distance of 416 to 826 million light-years, you immediately notice a huge structure that ...